Temperature control and measurement in IVF labs

How you measure and what you do with the information is critical

IVF laboratories commonly maintain operating and culture conditions within a narrow temperature range of 36.5 - 37.5 ⁰C. It is important to maintain this constant temperature, as prolonged periods could affect the development of the gametes and embryos and the quality of the culture media. Prolonged exposure of cultures to temperatures other than optimal 37 °C, reduces the ability of fertilization and greatly reduces the ability of cell division or cleavage, growth, implantation potential and subsequent achievement of pregnancy.

We found this excellent presentation by Jaco Geyer, from Vitrolife on the topic "The value of quality control and quality assurance - it´s in the details". In this presentation embryologist and former lab director Jaco Geyer from Vitrolife talks about the value of quality control and quality assessment. 

Thermodata understands how accurate temperature measurements underpin quality and regulatory compliance. Our small, precise and easily deployed T+ Buttons are calibrated to ISO17025 and facilitates your ongoing temperature monitoring activities.

The Thermodata system is flexible and scalable. You select your combination of hardware required and scale up the management of your processes on the Loggistix cloud service to fit in with your needs.

Here is some food for thought:

The information below reflects the temperature of an incubator over the last week, with data collected at 10 minute intervals.Graph of temperature in incubator
















  • The slight variation in temperature between the right and left side of the incubator is, in itself, not an issue or should it be?.
  • It is worth noting that the right side does trend consistently lower than the left side.
  • What are those spikes??? Read on …

The Daily Temperature Summary Report provides a quick view of the same incubator over the same period. It provides the daily highest and lowest temperature from 8.00 am to 6.00 pm, during operating hours when there is likely to be more activity, and from 6.00 pm to 8.00 am, when the lab is quiet.

Daily temperature report




























Interestingly, the minimum recorded temperatures occurred between 6.00 pm and 8.00 am … time for more analysis of the data…